Alzheimer’s: Lost Molecules From Food That Slow Brain Aging | Austin Perlmutter MD
The hidden data in food – and what it means for your brain health
There are an estimated 140,000 chemical signals in the food we eat. Most of us have never heard of them. But a growing body of research suggests they may be among the most powerful influences on how our brains age.
Dr. Austin Perlmutter, an internal medicine physician and researcher, joined “Vital Signs with Brendon Fallon” to explore what he calls the dark matter of nutrition—a vast universe of molecular compounds found in minimally processed plant foods that conventional nutrition science is only beginning to understand.
A study published in Neurology, the world’s leading brain health journal, has found that people who consume the highest levels of these molecules—known as polyphenols—have up to 48 percent lower rates of Alzheimer’s diagnosis compared to those who consume the least.
Which commonly consumed foods, like coffee, rank high on the polyphenol scale? How can you practically and affordably incorporate more polyphenols into your diet?
Dr Perlmutter is currently pioneering large-scale research into how food influences brain health – examining whether a specific polyphenol-rich food can measurably improve cognition, reduce inflammation, and alter epigenetic expression in healthy adults.
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Explore further brain health insights from Dr. Perlmutter here
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Dr. Perlmutter hosts the Get the STUCK Out podcast
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Related/Referenced studies:
Mediterranean diet is linked to a lower risk of stroke for women, a new study finds | Euronews
Mediterranean Diet and the Risk of Stroke Subtypes in Women | Neurology Open Access
Pattern of polyphenol intake and the long-term risk of dementia in older persons | Neurology
Dietary flavonols and risk of Alzheimer dementia | Neurology
Coffee and Tea Intake, Dementia Risk, and Cognitive Function | Lifestyle Behaviors | JAMA
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Further reading on diet for brain health:
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Vital Signs’ host, guests, and contributors offer general information on improving health and wellness. This is not intended as diagnosis or medical advice. You should consult your medical doctor or holistic doctor before enacting any suggested strategies for health and wellness improvement, including those in relation to preventing or treating specific diseases featured on this program.




