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If you’ve tried dieting, exercising more, and cutting calories—but the weight won’t budge and you’re exhausted from trying—the problem isn’t your willpower.
After 45, your body fundamentally changes. Estrogen drops. Cortisol spikes. Your metabolism slows down. And traditional weight loss approaches stop working because they don’t address what’s actually happening inside your body.
That’s why Arrae created MB-1 45+—a supplement specifically formulated for women in perimenopause, menopause, and beyond. It targets the root hormonal and metabolic shifts that make weight management, energy, and mood control so difficult during this stage of life.
Over 1 million bottles of Arrae’s original MB-1 formula have been sold worldwide. Now, MB-1 45+ refines that foundation with eight clinically-studied ingredients designed specifically for women over 45.

The Problem: Your Hormones Have Changed the Rules
Around your mid-40s, your body shifts in ways that sabotage typical diet and exercise efforts:
Estrogen Declines Lower estrogen levels disrupt insulin sensitivity, making it easier to gain weight—especially around your midsection. This hormonal shift also affects mood, sleep quality, and hot flashes.
Cortisol Rises Elevated stress hormones trigger belly fat storage, disrupt sleep, cause mood swings, and make it harder to manage stress effectively.
Metabolism Slows Down Your resting metabolic rate drops, meaning your body burns fewer calories at rest. What used to maintain your weight now causes weight gain.
Gut-Hormone Connection Changes The balance of hormones that signal fullness and regulate appetite gets disrupted. You feel hungrier, crave sugary or fatty foods, and struggle to feel satisfied after eating.
GLP-1 Levels Drop GLP-1 is a gut hormone that signals fullness and regulates blood sugar. When levels decline, appetite control becomes difficult and cravings intensify.
Traditional solutions don’t address these root causes:
- Dieting harder ignores the metabolic slowdown
- Generic supplements aren’t formulated for hormonal changes after 45
- Hormone replacement therapy involves synthetic hormones and potential side effects
- Exercise alone can’t overcome hormonal imbalances
The Solution: Target Multiple Pathways Simultaneously
MB-1 45+ addresses root causes by targeting key hormones and metabolic pathways that shift throughout midlife—supporting appetite regulation, weight management, estrogen levels, and stress response with clinically-studied ingredients.
Here’s how it works:
Activates GLP-1 Naturally The formula includes DygloFit, an ingredient that supports GLP-1 production—helping signal fullness, curb cravings, and balance appetite without injections or medications.
Reactivates Estrogen Through the Gut Gyntima probiotic blend supports your body’s natural estrogen, which can help ease menopausal symptoms like night sweats and hot flashes. This happens through the gut microbiome—no synthetic hormones required.
Reduces Cortisol Levels KSM-66 Organic Ashwagandha is a clinically-studied adaptogen that lowers stress hormones. This helps improve mood swings, enhance sleep quality, and combat cortisol-related belly fat accumulation.
Balances Leptin and Adiponectin These hormones regulate fat cell size, appetite, and cholesterol levels. When balanced, your body can shrink fat cells more effectively and maintain healthier cholesterol levels.
Increases Resting Metabolic Rate Grains of Paradise boosts thermogenesis—the process by which your body burns calories to produce heat. This means you burn more calories even while resting.
Reduces Fat Production IGOB131 helps reduce fatty acid production to support healthy triglycerides and LDL cholesterol maintenance.
Supports Blood Sugar Regulation Chromium enhances insulin function and glucose uptake, which helps curb cravings and stabilize energy levels throughout the day.
Regulates Mood and Water Retention Vitamin B6 in its most bioactive form (Pyridoxal 5-Phosphate) supports protein metabolism, reduces water retention, and regulates serotonin for emotional balance.
What Users Experience
Month 1: More Consistent Energy and Fewer Cravings Within the first month, many women notice reduced appetite, fewer intense cravings, and steadier energy levels throughout the day. The afternoon crash becomes less severe.
Month 2: Improved Sleep and Stress Management As cortisol levels balance and hormones stabilize, sleep quality improves. Mood swings decrease. That constant feeling of stress and anxiety starts to lift.
Month 3 and Beyond: Visible Weight Management Results By the third month, metabolic changes become more apparent. Weight management becomes easier. Body composition improves. Hot flashes and night sweats may decrease in frequency and intensity.
The formula is designed as a three-month system that works with your body over time—not a quick fix that provides temporary results.
Why It’s Different From Other Supplements
Specifically Formulated for Women Over 45 Unlike generic metabolism boosters or standard menopause supplements, MB-1 45+ takes a comprehensive approach. It targets multiple mechanisms simultaneously—GLP-1, estrogen, cortisol, leptin, adiponectin, and metabolic rate.
No Synthetic Hormones The formula uses plant extracts, probiotics, and nutrients to support your body’s natural hormone production. No injections. No prescriptions. No synthetic hormone therapy.
Clinically-Studied Ingredients Each ingredient is backed by research demonstrating effectiveness for the specific challenges women face during perimenopause and menopause.
Built on Proven Success MB-1 45+ builds on the foundation of Arrae’s original MB-1 formula, which sold over 1 million bottles worldwide. The new version adds targeted ingredients for hormonal shifts, stress management, and menopausal metabolic changes.
Clean, Quality Standards Arrae is known for clean, high-quality supplements. The brand has built a reputation for products that work—like their cult-favorite bloat capsules found in bathrooms from Malibu to Montauk.
How to Use It
Take two capsules daily in the morning with a protein-rich meal. Consistent use for at least three months is recommended to support best results. The supplement works progressively—supporting your body’s natural rhythms over time rather than forcing quick changes that don’t last.
The Bottom Line
Weight gain, cravings, low energy, poor sleep, and mood swings after 45 aren’t personal failures. They’re biological responses to hormonal shifts that traditional diet and exercise approaches can’t fix.
MB-1 45+ addresses the underlying metabolic and hormonal changes causing these symptoms—without synthetic hormones, injections, or extreme restrictions.
For $69, you get a one-month supply (60 capsules) of a formula backed by clinical research and the trusted Arrae quality standard. Subscribe and save options provide additional discounts and ensure you never run out.
Arrae offers a 30-day money-back guarantee. If the product doesn’t deliver the expected benefits related to metabolism, digestion, cravings, or overall wellness, you can request a full refund within 30 days of purchase.
Free shipping across the US and Canada is included.
If you’ve struggled with stubborn weight, exhausting cravings, and feeling unlike yourself during perimenopause or menopause—this formula targets the biological reasons why.


























