The World Health Organization (WHO) and partners are sending 70,000 doses of an Ebola vaccine to Congo, filling a request from the central African country that is dealing with the second-deadliest Ebola outbreak in history.
Merck’s Ervebo, the Ebola vaccine, is cleared for use against Ebola caused by the Zaire ebolavirus. Congo’s growing Ebola outbreak is caused by the Bundibugyo ebolavirus, for which no vaccines are approved.
Congo requested doses of Ervebo, and the International Coordinating Group on Vaccine Provision, a coalition of four groups that stockpiles and offers vaccines upon request, approved an initial release of 70,000 doses, according to the WHO, one of the groups.
WHO Director-General Tedros Adhanom Ghebreyesus said in a statement that the approval was “an important example of global solidarity in action.”
Some 20,000 doses will go to a previously announced phase 3 clinical trial that will assess the efficacy of the vaccine against the Bundibugyo virus. The rest will be for frontline and health workers.
It’s not clear whether Ervebo works against the Bundibugyo virus, the WHO noted, although preliminary laboratory and animal data “suggest it may provide some protection.”
“It is key that the people offered the vaccine, in the trial and otherwise, receive information of the risks, potential benefits and limitations related to the use of the vaccine in an outbreak of Bundibugyo virus and are able to provide informed consent,” the WHO stated.
The other coordinating group members are Doctors Without Borders, the Red Cross, and the United Nations Children’s Fund.
The International Coordinating Group stockpiles vaccines and releases them to countries facing epidemics, provided the requests meet certain criteria, according to its website. For approved requests, the target is to deliver doses within 10 days.
The Ebola outbreak in Congo was detected in mid-May. The outbreak started earlier. A delay in detection stemmed from initial testing being unable to identify the Bundibugyo virus, authorities have said.

“The response is being strengthened, notably through vaccination with ERVEBO and intensified surveillance and case management in the affected areas,” Congo’s Ministry of Communication and Media said in a post on X.

Congo has never dealt with a deadlier outbreak of Ebola. The deadliest Ebola outbreak in world history took place in West Africa from 2014 to 2016, killing more than 11,000 people.

